Gonna do about 2-3 weeks of low fiber, very low sugar diet.
Gonna not work & do meditation, and just try to stay positive & upbeat. Cause the mind can have health effects also.
Gonna supplement with caprylic acid, something I never took before. Gonna take it heavy for the 2 weeks. May also take
lactoferrin supps, and may drink raw milk before or may wait till after.
Gonna stop all supps 2 days before & juice fast for 2 days prior. Gonna try & do 10 fecal transplants not all in a row but spread out for awhile. Maybe first 3 in a row.
Wasn't planning on injesting, but may decide to do after the midway point.
After the first transplant, gonna start more high fibre foods & gonna drink raw milk, eat sauerkraut, drink aloe vera juice to heal intestines if necessary, gonna juice cabbage juice again for the intestines, and gonna keep trying to eat fairly clean for awhile.
I guess thats it. Anything I should add or take out of my protocol?
Markk,
Let me give you my thoughts again. You don't need to do most of the thing you want to do. (IMO) HPI has demostrated to be highly effective. First, you don't need to take Caprylic Acid. Caprylic Acid is a natural antibiotic. Anything that says acid should be avoided. The only thing you need to do is to take a PPI one day before and the morning before the procedure. Only two tablespoons of the human bacterial solution is effective to colonize the gut. This procedure has been effective in any way people have done it. The diet won't make any difference.
It is really simple. If you want to repeat the procedure several times, it is all to you but one time is really effective. The most important is the donor flora quality. Some pioneers Drs in this matters claim the oral way is more effective. Remember, colonics won't cover the small bowel. The donor flora will take hold in your gut, so you will win new species and will increase most of your own.
Jorge
I agree with djorge on the caprylic acid. Of course I would avoid sugars and refined carbs. You may have success with one implant, then again it may take 4-5. Please keep us posted. I am still looking for a donor. Not something most people are going to understand. Good luck and thanks for the good info you have provided us about HPI.
I thought you were gonna try & eliminate your candida somewhat before doing the procedure. I have candida and klebsiella, both of which tested suseptible to caprylic acid.
Thats why I was gonna take that, to hopefully knock down
both of those bad organisms.
Also, stomach acid kills about 80% of probiotics. I assume injested human probiotics will be killed about the same. I don't wanna take a PPI, i'm alittle concerned about that. I don't like to take things that "trick" my body. I was gonna injest possibly if the enema way didn't work.
What do you think should be done to make it palatable?
Markk,
The PPI is the most important. You need to shut down your parietal cells before to do the HPI. What you want to do isn't a HPI but a rectal Fecal Transplant. In this way, you don't need a PPI. Keep in mind that colonics will feed the colon but not the small bowel. Think that most Drs have done the HPI to cure C. Difficile using a nasogastric tube. You don't need to take antibiotics because the flora you adquire is strong enough to overcome the pathogenic bacterias. In the case of C. Difficile, it isn't kill and repopulate but bacterial dominance adquired after the implant. What have the power of curing a C. Difficile infection isn't the antibiotics but the human indigenous bacterias you get from the donor. If you stop Caprylic Acid some days before the implant, it probably works well. After the implant, you should avoid anything with antibacterial effects. Again, the most important is that the donor has a good flora. That is what really make a difference.
Jorge
Human strain beneficial bacteria need to be able to survive stomach acid. Without that ability, they never would have gotten there in the first place.
OTC probiotics die because they're mostly not human strain.
True human strain probiotics can be taken as a liquid.
I imagine that in reality, some of the HPI will die in the process, and that's why the PPI's are recommeded. But like Cheshire77 states, it will probably work however you do it if the donor bacteria are good.
Oral administration makes more sense to me, just to ensure it gets established in small intestines.
Tony,
Bacterial colonization of the human gut ocurr during the first 6 months of life. Babies don't have an strong immune system before the 6 months of life. Curiously, the stomach acid production is linked to an active and healthy immune system. So, I realize that the parietal cells in babies won't produce high amount of stomach acid until the immune system be totally developed. Probably a mother nature mechanism to assure gut colonization by bacterias. People with HIV don't produce stomach acid because the immune suppression. I don't say that some bacterias can not survive the stomach acid later in life but the massive colonization ocurr during the first months.
Jorge
Seriously, Your approach sounded awesome already-- and IM very impressed (please DO keep us posted)
The idea of Caprylic Acid is smart to reduce the load of Candida- very simple idea, very smart. I however would add at least a TBSP of Pysllium fiber once a day (A) It will reduce the crazy die off that might occur, & (B) will help get the yeast scraped off and out of the intestines a bit.
I personally believe with candida you definitely get reduced stomach acid. With that said- Obviously, do a fecal transplant on an empty stomach with lots of distilled water. it WILL bypass stomach acid. If the sample is new and Viable, it will be effective. The PPI is optional I guess.
You're the smart one who got the sample, you're not all talk, you have the balls to do it, so do what YOU want.
If I was doing it, I would try and make real sure that I had eradicated as much of the candida as possible first. I would go with a stronger protocol for a longer duration.
The professionals who treat C Diff/UC, ask you to try and eliminate as much pathogen as possible prior, up to 3 rounds of antibiotics.
I would tend to carry that thinking over to Candida.
The HPI is going to need free space in order to implant. That means getting rid of as much candida as possible, as well as other misfit/pathogenic bacteria.
Also, I would give the antifungals/antibacterials a chance to clear out before doing the HPI.
Then do as Jorge recommends with the Proton Pump Inhibitors.
But, we don't have a lot of data from candida sufferers who have tried this, so it would be interesting to see if the implant took in a candida dominated gut. I would expect it to fail, but if it's not costing you anything, it might be interesting to try.
Anyway, I wish you success on this and will follow your updates with interest.
The bacterias from the donor will take residence in your intestines in any way. They probably will implant better if you don't take antibiotics prior the procedure. The necessity to create space is a myth. It is demostrate how resilient our flora is, and they will colonize in any way.
According to an information I got, candida levels disappeared in stool culture only one week after the transplant. I am not sure this will happen in every case but I hope to get the biggest benefit of it. So far, the only possible way to get a human indigenous flora back after antibiotics is this one.
Maybe its not about creating space, but just knocking down
bad bacteria so there's less competition in the intestines.
Really hard to say, everyone seems to have a different opinion.
Nobody can give you a definitive answer. It is experimental and new. We have to follow the experiments and scientific evidences. Rats that were given antibiotics were less receptive to adquire the donor's flora, insted those rats that weren't given antibiotics adopted a more bacterial diversity from the donors. This is pretty good evidence that the flora implant better without antibiotics.
Mark, I've reviewed all the HPI data in the last week because I anticipate doing my own HPI very soon. As you say, opinions vary, however after reviewing lots of scientific and anecdotal reports, I have formed the opinion that it doesn't really matter how you do it. These stool bacteria seem to colonize very well given half a chance. I don't think it is necessary, or even advantageous to take anything to kill bacteria before HPI. I also don't believe it helps to do a lavage or anything else to 'make space'.
Even factors like how much stool you use, how often you do it, whether you use oral of enema, whether you use saline solution, milk or even tap water.... none of these things are critical to success. However, the one thing that is very important, is the quality of your donor stool. Doing it once with a good donor is better than 100x with a poor donor.
Theoretically, there should be a market for stool donors, with premium dollars paid to happy, healthy, slim donors, because all these qualities are heavily influenced by our bowel bacteria. I really wish the medical and scientific professions would 'get over' the yuck factor, and fully research bowel bacteria transfusions. If they did, before long there would be refigerated probiotics available that actually colonized the bowel, and cured lots of diseases. This would prevent enormous misery, and save trillions of dollars. Doctors could then prescribe healthy colonizing probiotics to be taken with, and after, ABx.
Interesting. Could you point us to some of your sources.
Also, are you saying that a gut dominated by Mycelial Candida will return to normal after HPI? Or are you strictly referring to Misfit/Anaerobic bacteria.
Finally, when you say "given half a chance" what are you referring to? That is to say, in the research you did, what emerged as factors that limit/impede the success of HPI?
Also, are you saying that a gut dominated by Mycelial Candida will return to normal after HPI? Or are you strictly referring to Misfit/Anaerobic bacteria.
No, I'm not saying a gut lining infested with mycelial Candida will return to normal. Once Candida has a strong hold, it is hard to dislodge. But there is no doubt certain bowel bacteria inhibit Candida, so it is a step in the right direction. Hopefully these bacteria will also help prevent relapse once you do get on top of Candida.
Finally, when you say "given half a chance" what are you referring to? That is to say, in the research you did, what emerged as factors that limit/impede the success of HPI?
Like I said in my post, the only thing proven to be important is the quality of donor stool. Other factors may or may not contribute to a good HPI, but are unsupported by the facts I have seen. By 'half a chance', what I mean is that stool bacteria readily implant, and one doesn't need to get bogged down trying to formulate the ideal protocol. As Nike says, just do it!
While I'm open to your ideas, the study you cite does not support your claim that trying to clear out pathogens prior to HPI is a "myth."
The study doesn't even use sick rats. Doesn't mention pathogens such as Candida Albicans, C. Difficile, or H. Pylori, etc. And it only uses a single procedure. While, as Blackwater states, it sometimes takes several attempts.
The study indicates only that antibiotics given to rats before fecal implantation results in a gut flora profile midway between the healthy donor rat and the rats given only antibiotics.
So, I would just say, while I appreciate your passion on the subject, be careful what conclusions you draw from studies such as these. If you have another study that supports your statements, I welcome it.
While I support HPI, I would not say that it's the only way to restore gut Flora. I would agree that it's the fastest and best way.
Please consider that claiming that it's the only way is A. Unprovable and B. Discouraging to others who are attempting to do it the slow way, through diet and attention to intestingal health and proper acidity.
One thing is the rats that took antibiotics prior to the implant took the antibiotics up to the day before. That to me doesn't necessarily suggest that taking antibiotics for a few weeks up to say 1 week before isn't effective. I think taking antibiotics the "day" before will leave a residue behind that will kill bacteria after you cease taking them. how long that residue last? I dunno?
Secondly, you guys keep saying that it doesn't matter about this or that. But the cdd in Australia has performed this procedure the most by far, and they have the most experience with it. Everyone is just going to discredit everything they say?
They talk about a low fiber diet before, and also knocking down bad bacteria before & clearing space with a lavage.
They also repeat the procedure many times.
I'm just wondering why you give no merit to there protocol
I agree with you. I would learn as much as I can from the people actually doing it, professionally. Anecdotal cases are interesting, but not always reliable.
Their procedures may be overkill in some instances. But in my mind, if you do the procedure only to find that you now have to take antibiotics to get rid of an H.Pylori infection, or some other infection, what was the point?
Cheshire77 may be right, but I need to see more evidence.
I think taking antibiotics the "day" before will leave a residue behind that will kill bacteria after you cease taking them. how long that residue last? I dunno?
I agree. I made this point a few weeks back when this study was first posted. I think the study was flawed in that they gave ABx the day before HPI and didn't even flush the bowel, so I think it highly likely there was ABx residue. It's a shame they made this mistake because otherwise their conclusion (re ABx) would have been very helpful. Nevertheless the study did show that ABx were not necessary for a very good outcome.
Secondly, you guys keep saying that it doesn't matter about this or that. But the cdd in Australia has performed this procedure the most by far, and they have the most experience with it. Everyone is just going to discredit everything they say?
I am very familiar with the CDD protocol, having done it in Sydney. I think they have always used ABx, because Prof Borody comes from a background of killing bugs with ABx. These guys just assume it is necessary, because they have never tried it without ABx. All their training and professional experience has involved ABx. They find it hard to accept that maybe ABx are not good for you. Besides, they have a healthy little earner going with their program. Prescribing ABx and running 5-10 day programs at great expense. It is not in their interests to go around saying you can do it once at home by swallowing a little poo or doing one enema. No-one would need to pay for their program. Those in research and specialist fields of medicine are ego driven. The more you are reliant on the specialized services only they can provide the more important they feel. Another reason is that their protocol is more likely to be accepted by medical publications and their peers if they use antibiotics and have a specific regimented protocol. Makes it look professionally acceptable.
The most important part of the rat experiment is the transplant was successful without to use antibiotics. The donor flora became dominant after the procedure. It shows antibiotic aren't required at least you need to eliminate a bacterial pathogen. In the case of C. Difficile, it isn't necesary bacause the new adquired flora is able to suppress it. Not sure if this will be the case for any bacterial pathogen.
Jorge
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My HPI protocol... any thoughts 
Re: My HPI protocol... any thoughts 
