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Weight loss and exercise reduce cancer markers in women

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  • Weight loss and exercise reduce cancer markers in women by  #136970  12 mon  1,231  News / Cancer Sup / Exercise / 4

    This study by the Fred Hutchinson Cancer Research Center in Seattle discovered that by losing at least 5 percent of their body weight and exercising while doing it, women significantly reduced markers for cancer.  Then below that story is the one that was posted yesterday that joggers (light jogging) increased their life span by six years.  These are both studies that show that getting off one's butt and becoming active is more beneficial than "taking a pill" or otherwise self medicating is much more beneficial than satisfying our oral demands.

    http://news.yahoo.com/weight-loss-reduces-cancer-risk-overweight-women-141052348.html;_ylt=A2KJjb3mnqZPzjYAukfQtDMD

    Weight Loss Reduces Cancer Risk in Overweight Women

    Overweight or obese women who lose at least 5 percent of their body weight may lower their levels of the type of inflammation linked with cancer, according to a new study.

    The findings show that women who dieted, exercised and lost weight saw their levels of an inflammation marker called C-reactive protein drop by 42 percent, and lowered their levels of another inflammation marker linked to cancer, called interleukin-6, by 23 percent over the course of a year.

    "Both obesity and inflammation have been shown to be related to several types of cancer," said study researcher Dr. Anne McTiernan, of the Fred Hutchinson Cancer Research Center in Seattle. Studies have linked obesity to an increased risk of cancers of the endometrium, colon, pancreas and kidney. Development of as many as 25 percent of cancers is likely facilitated by a sedentary lifestyle and higher-than-normal body weight, McTiernan said.

    The decreases in inflammation seen in the study were larger than anti-inflammatory medications would produce, McTiernan said. Researchers believe that inflammation damages tissues and organs in the body — damage that can result in cancer development, or the progression of existing cancer, she said.

    The findings "reinforce the importance of weight control on biomarkers that not only have strong associations with cancer, but also with other prevalent chronic diseases, such as cardiovascular disease," said Wendy Demark-Wahnefried, of the University of Alabama Comprehensive Cancer Center in Birmingham, who was not involved in the study.

    The study is published today (May 1) in the journal Cancer Research.

    Cancer and weight loss

    The study looked at 439 overweight and obese post-menopausal women. The women were assigned, for one year, to either a calorie-restricted diet, exercise, or both. The goal for each participant was to reduce their body weight by 10 percent. The researchers ran blood tests to measure the women's levels of inflammation markers.

    Women who dieted, but were not assigned to exercise, saw drops in inflammation similar to those of the women who dieted and did exercise, the findings showed.

    But exercise alone did not affect inflammation levels — a finding that did not surprise McTiernan. Previous studies showed that exercise only reduced inflammation if the person lost a significant amount of weight, she said.

    It seems to be that the loss of fat is the critical issue, she said.

    Dr. Tim Byers, associate director for Cancer Prevention and Control at the University of Colorado Cancer Center, agreed. "It’s really not surprising that body weight and the amount of weight loss determines the changes in these circulating inflammatory factors," he said.

    However, while higher levels of inflammation are associated with an increased risk for certain cancers, a cause-and-effect link between increased inflammation and cancer has not yet been fully established, the researchers noted. According to experts, other obesity-related factors besides inflammation, such as levels of blood sugar and sex hormones, can also increase cancer risk.

    What women can do to lower their cancer risk

    McTiernan said that women who are overweight should first stop gaining weight, and then increase their physical activity. "At least 150 minutes or more per week of moderate or vigorous level activity — this is what is in the national guidelines," she said.

    Women need to get a handle on what they are really eating, she said. Using an online calorie-counter program or old-fashioned food log should do the trick. "Most women should be taking in less than 2,000 calories per day, unless you're an athlete."

    For weight loss, a realistic goal is losing one to two pounds a week, and to aim for a 10 percent reduction over a six-month period, McTiernan said.

    Large benefits can be expected with even small amounts of weight loss, Byers said. He advised keeping up with exercise to maintain a normal body weight.

    Both Byers and Demark-Wahnefried said the results of the study are not restricted to postmenopausal women. "The current data suggest that maintaining a healthy weight over the entire life course is important, regardless of gender," Demark-Wahnefried said.

    Pass it on: Losing weight can lower levels of harmful inflammation, and could decrease cancer risk.

     

    The corollary to the above study is this one:

    http://www.marieclaire.co.uk/news/health/536113/jogging-adds-five-years-to-your-life.html

    Jogging adds five years to your life

    By Maz Khan on Friday 4 May 2012

    Regular, gentle jogging can extend our lives by approximately five years, according to new research.

    Chief cardiologist of the Copenhagen City Heart Study, Peter Schnohr, found that an hour of gentle jogging a week could benefit our hearts even more than an intense run.

    ‘We can say with certainty that regular jogging increases longevity. The good news is that you don't actually need to do that much to reap the benefits.'

    ‘You should aim to feel a little breathless, but not very breathless,' he added.

    The study looked at 2,000 joggers and found that women who jog at a slow or average speed could extend their life by an average of 6.2 years.

    Experts say this impact of jogging on life span is linked to the demand of gentle physical activity on our stamina.

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    • Re: Weight loss and exercise reduce cancer markers in women by  Dquixote1217  12 mon  956

      The  benefits of exercise and leading an active lifestyle are pretty much indisputable.  When it comes to losing weight, that too is generally a very healthy thing to do - but it should be pointed out that the foods one consumed which lead to being overweight were likely more important than the excess weight itself and that the food one consumes to lose weight and maintain a health weight are also important.

      As people in the mediterranean have amply demonstrated, one can have excess weight and still be be very healthy and lead long lives - provided that the excess weight came from an apetite for healthy, nutrient dense foods and that one still manages to be physically active.

      In other words, do not lose weight simply by cutting back on crappy foods.  Cut those foods out altogether, switch to wholesome nutrient dense foods and get off the sofa and be more active.  If you do, you chances for cancer and other disease will be less and your odds of living longer will be greater.

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      • Re: Weight loss and exercise reduce cancer markers in women by  #136970  12 mon  943

        While your response "seems" logical, it really isn't.  In another "news" post I've made about a very recent study in Denmark that covered a 30 year period of time, light jogging for anywhere from 1 to 2 1/2 hours a week increased the lifespan in males by 6.2 years and in females by 5.8 years.  There was no correlation with food ingestion at all.  None!

        Americans in particular have an oral fixation - for a couple of reasons.  #1 is that the vast majority of us (myself included) were never allowed to do such a "horrible" thing as suck on a tit.  In American culture we still have the stupid idea that the breast is a sexual object (it isn't) and there are stories almost weekly of women being forced to move or cover up while breast feeding in a public place.  #2 is that with the bottle readily available when a small child starts fussing the rubber nipple is jammed into their mouths to keep them quiet.  Very few of us were properly fed as children which allows all the fast food and other food advertising to get to us.

        In the study you are responding to, it was shown that diet for weight loss along with exercise reduced cancer markers and the incidence of all disease well beyond cancer alone.

        "The findings "reinforce the importance of weight control on biomarkers that not only have strong associations with cancer, but also with other prevalent chronic diseases, such as cardiovascular disease," said Wendy Demark-Wahnefried, of the University of Alabama Comprehensive Cancer Center in Birmingham, who was not involved in the study."

        When a person here on CZ asks for help in dealing with a physical issues they receive many different ideas for "taking something" to improve their condition.  That's our oral fixation and you do it all the time.  Nowhere is there a voluntary standard here on CZ to even provide information that every physician receives (but not chiropractors for example) on a routine visit for health issues and those things are: weight (Body Mass Index); activity levels; tobacco usage; alcohol consumption; and of course even gender - all of the information that an MD uses before even talking to a person.  But no - CZ responders all have an oral fix for every poster and many of them even conflict.  

        Again the OP in this thread was showing that losing weight and exercising significantly reduce cancer markers.  And like unto it, the study in Denmark about jogging indicated a 6 year life extension for doing so.  There was no mention anywhere in either of those posts about what the study members ate.  Jogging not only produces life extension but the endorphins produced by jogging gives a sense of well being that pills/oral ingestion cannot provide.  I'm just as lax as others because my knees wore out about six years ago and I had to quit joggin, but I can still walk and I still do.

        So - Jim Fixx and others have died while running.  So what!  Bet you a bundle that he was one happy camper when he went.  Nobody but nobody's body is immortal and if we can face death and laugh in its face we would all be better off because someday it's going to take you and me and everyone else on the Planet.

        Getting off your butt and moving whether it is walking or running will do far more than anything else to benefit your health.

        Here's a great story related to this thread:

        http://www.huffingtonpost.com/2012/05/07/obesity-america-20-year-forecast-epidemic_n_1496439.html

        Obesity In America: 42% Estimated To Be Obese By 2030, New Data Shows

        05/07/12 12:10 PM ET

        WASHINGTON -- More bad news about Americans' waistlines: They're only going to get bigger.

        Already, about a third of people are obese. By 2030, it is estimated 42 percent of the population will be......

        (more at the site)

         

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        • Huh? by  Dquixote1217  12 mon  878

          I am wondering where you got the idea that anything I posted suggested that exercise did anything but extend lifespans or that I have ever not hugely supported healthy lifestyles and diets?  Quite the opposite, and I would further say that all the supplementation in the world is not likely to do you very much good without a healthy diet and lifestyle.  In fact, here is the article I wrote about building a healthy foundation for better health and longevity - and one I very often refer people to:

          http://www.tbyil.com/healthy_foundation.htm

          Perhap some people here just have a hard time when anybody responds to something they post which does not completely echo what was posted?  I don't think that what I posted was contrary to your post at all - more like complimentary, or at least supplementary (no pun intended).

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          • Re: Huh? by  #136970  12 mon  867

            I'll stand by the post that I was responding too.  EVERY post of yours that I've read always recommends "taking" something and more often than not - something that you happen to sell.  It's like combining the AMA with the FDA - the one's that you constantly complain about.

            I'll also stand by the inference I made in that post that it isn't nearly so much about what you eat, it's about your weight, and your activity level.

            I remember about a year or so ago that a guy in the Bay area was at 114 the oldest living person on the Planet (he has since died) who ate ice cream and bacon on a daily basis.  My aunt who finally tired of living and joined my uncle who died at 99, also ate bread, butter, and bacon for breakfast - almost daily, when she died at 100.  Your version of eating properly and other peoples version is often very different.

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            • Re: Huh? by  Dquixote1217  12 mon  835

              Something I sell? The only think I sell is two e-books.  My website and web efforts are supported by affiliate and sales advertising, the same as this site and most sites on the web.  One difference is that I am quite picky about what products and companies are advertised in connection with my site and efforts.  One thing you will almost never see here in any of the public forums is a link to a product which I am connected with in any way.

              I do think that supplements can be very useful in correcting existing problems and in addressing deficiencies, but overall they are no substitute for a healthy foundation and no one should come to depend heavily on a bunch of supplements for longterm health.

              Otherwise, I agree with you about activity level and disagree about the importance of what you eat.

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              • Re: Huh? by  #136970  12 mon  885

                "Something I sell? The only think I sell is two e-books."

                In your "Huh?" post you posted a link to your sales site which is filled with "remedies" that you sell.  Here's but one small example and I don't have time to browse the rest of the links at that site.

                http://www.tbyil.com/ADD_ADHD.htm

                "Perhap some people here just have a hard time when anybody responds to something they post which does not completely echo what was posted?"

                You're actually the one who becomes verbally violent when things are posted by others.  An example is when someone posts a link to an obvious sales site you rant and rant and ask for the moderator to remove the post.  Yet when you post a link to your site, as you did in "Huh?" - you see nothing wrong with it.  It's like to pot calling the kettle black.

                I'm not an anti-Tony guy, in fact I've given many of your posts positive ratings - you supply excellent information from time to time.  The one thing I'm pushing in my recent posts is to get down to your better weight - your BMI of 25 or less, and zillions of your real and supposed ills will disappear.

                Japan is the leading country for longevity (http://geography.about.com/library/weekly/aa042000b.htm) - not a Mediterranean country.  By the way (http://www.nationmaster.com/graph/hea_obe-health-obesity), in obesity the United States is #1 at 36%, Italy (which you referred to as having excess weight) is #25 at 8.5%, and Japan is #28 at 3.2%.  So your earlier statement that "one can have excess weight and still be be very healthy and lead long lives" is simply not true.

                Get down to a BMI of 25 or less and you'll not only be a lot healthier, but happier too.  You too Tony.  You can't do it through diet alone, though it helps, we all need to get off of our butts and burn the fat off.

                 

                 

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                • Re: Huh? by  chrisb1  12 mon  885
                  136970,
                  your comment..........

                  "The one thing I'm pushing in my recent posts is to get down to your better weight - your BMI of 25 or less, and zillions of your real and supposed ills will disappear".

                  Is a sweeping generalization and only partially true. Obesity is a risk factor in many diseases, not least of which are cancer and Diabetes, but I have known of many people throughout my 59 years who were lost to me when of an ideal weight or BMI: my father for one, and my best friend for another. I also had Leukemia when well within my ideal BMI.

                  The actual correlation between disease/longevity and health, is actually toxemia/nutritional deficiencies and an adulterated processed diet. The SAD confirms this with disease amongst Americans, which is increasing decade after decade.
                  In over three decades of work, researchers have not clearly supported a direct, positive, and causal relationship between weight and morbidity/mortality..................
                  http://www.jonrobison.net/FDNH/unit1c_c.htm


                  Chrisb1.

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                • Nope! by  mo123  12 mon  853
                  You are way off base and first he is the moderator here and he can post whatever he wants and second he lets me post my links all the time to my cancer books, reviews on Bollinger and my links to selling nigella sativa.

                  He bans people who come here with one link or thread only to sell their miracle cures. As usual Tony receives a bad rap for things people do not know what the hell they are talking about.

                  Sara

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                  • Re: Nope! by  Dquixote1217  12 mon  968

                    I am the local moderator of the Cancer Alternatives support forum, not the news forum this thread originated in.  I don't generally allow sales links in posts in the cancer support forum - maybe I missed yours and you lucked out?  As far as I know, your posts which originated in the Cancer forum were primarily informational and contributed to the purpose of the forum and were not posts whose purpose was to promote selling anything.  When links appear in posts which I consider to be primarily sales links, then usually I simply edit out the links.

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                • Re: Huh? by  Dquixote1217  12 mon  820

                  My website is primarily an informational website which supports itself with sponsor/affiliate links and advertising - the same as is true with this website and with numerous other websites which are considered first and foremost to be informational websites.  The primary thrust of my website by far is information and not pushing any particular product. 

                  There is a very great difference between an informational website which supports itself with advertising and a site which was created to sell one or more products - just as there is a very big difference between a link to an informational article and a link to a page which may contain information but whose primary thrust and content is to sell a product or service.

                  The issue of whether my website is an informational website or a promotional website has been addressed and settled here as well as other websites where people have raised an issue (though it happens infrequently, there are times when people try to use it as an accusation to further their points of views and demean mine, or as seems to be the instance with you, times when people cannot handle anyone posting anything which does not echo what they have posted) - including for example, Yahoo Answers, where they have a strict policy against links to sales promotion sites.  It has always been determined that my website is primarily an informational website.

                  If you choose to disagree, certainly that is your right - but your opinion is not shared by other sites nor is it shared by the owner of this site - and in the final analysis, that is whose opinion counts most here.

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            • Re: Huh? by  chrisb1  12 mon  859
              136970,

              I agree with DQ here.

              Exercise is vital for health/longevity, as is the fuel/nutrition you place into your body, along with fresh air, ample rest and sleep, freedom from stress, and pure water. Hygiene, both personal and environmental are also of vital importance in longevity markers.

              It is only in recent years that Mainstream has twigged onto the idea that all the elements for health provided by Nature are of equal importance, and what was endorsed by alternatives many decades ago, is now catching on. The body is after all a holistic organism and if treated as such, reaps good health and freedom from disease, especially chronic diseases such as cancer.
              If you are unable to jog yourself, then you may wish to try rebounding, which according to NASA is 68% more efficient than jogging alone.
              Also the PACE exercise programme, endorsed by a Harvard Study and Dr Al Sears MD, is simply the best exercise in existence.
              Aerobics and Cardio are dead.............
              http://www.alsearsmd.com/pace2/jvnb/


              Longevity can be increased in a number of ways, and not only exercise, as evidenced by Luigi Cornaro who lived from a frugal and low calorie diet, and lived an active life to the ripe old age of 102. He did not include an exercise regimen at all................
              http://drbass.com/cornaro.html


              PS. DQ is not a salesman, but a health writer/researcher, so you are barking up the wrong tree on that score.

              Chrisb1

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    • Re: Weight loss and exercise reduce cancer markers in women by  explorer2009  12 mon  1,041
      This doesn't seem a revelation as cancer has basic energy of Cold = Yin.
      Physical exercises are Yang.
      Excess body weight is Yin syndrome, so losing weight
      is shifting to more Yang.

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    • Re: Weight loss and exercise reduce cancer markers in women by  jameseclark  11 mon  755
      overweight post-menopausal women who exercised for 45 minutes 7 days a week. Moderate weight loss reduces levels of Breast Cancer . specifically look at the effects increased physical activity and weight loss have on reducing the chance of getting cancer.

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