Hello Jim,
Since diet is the cornerstone,I would guess you changed something from your previous
diet where the results were good.How many bowels of brown rice,what kind and amount of vegetables?Are you still taking the same medications? Maybe the stevia or yogurt? Are you also eating some of the previous procedure diet foods? This sudden reversal was caused by some outside physical change.Maybe some over activity.I don't believe the change was small and this is a good opportunity to narrow down a probable cause of your past problems.Since you colon is in a very irritated condition,any negative activity would give a bad responce.sheldon
I am eating 1/4 of brown rice 3x a day, 3/4 cup of mixed steamed veggies (parsnips, turnip greens, califlower, red/orange peppers, squash, carrots), 3 tablespoons of pearl barley, and mix it up with Salmon and chicken. (this is used for all 3 meals)
The only thing I added in was the plain yogurt which I will refrain from using.
It has been a pretty hectic week preparing for vacation so the stress levels have definatly been elevated. As of this morning I am feeling a bit better so I feel the issue was a combination of stress and the yogurt.
I have been reading through past posts and am very impressed by the time you have committed to helping others to heal themselves.
I am considering this procedure and was just wondering what diet choices you would recommend for someone who follows a vegan diet? Are any beans/legumes allowed on your plan?
Hello,
Use the basic procedure vegetable and grain diet at first.If done correctly,you should get a positive response within a week.You can use this basic response to test other foods one at a time.However,I would wait a couple of weeks to give the colon irritation a chance to subside.Please keep us posted.
A novel water-soluble vitamin E derivative protects against experimental colitis in rats.
N Yoshida, T (Takeo) Yoshikawa, T Yamaguchi, Y Naito, T Tanigawa, H Murase, M Kondo
This study was designed to investigate the effects of water-soluble vitamin E derivative, 2-(alpha-D-glucopyranosyl)methyl-2,5,7,8-tetramethylchroman-6-ol (TMG), on experimental colitis in rats. Colitis was induced in male Wistar rats weighing 200 grams using an enema of trinitrobenzene sulfonic acid (TNBS) dissolved in 50% ethanol; 1 ml of TMG dissolved in physiological saline (0.2 mg/ml, 2 mg/ml, 20 mg/ml) was injected intraperitoneally every day for 1 week after the enema. The damage score, wet weight of the colon, and increase in body weight were estimated 1 week after the enema of TNBS. Thiobarbituric acid-reactive substances (TBA-RS), an index of lipid peroxidation, and the level of alpha-tocopherol or TMG in the colonic mucosa were measured 1 week after the induction of colitis. As a result, increase in body weight was inhibited by the induction of colitis, although the inhibition was reduced in the group treated with TMG. The damage score, wet weight and TBA-RS were increased significantly in the colitis group; however, they were inhibited by the administration of TMG. The alpha-tocopherol level in the colonic mucosa was reduced by the induction of colitis, wheres TMG could not be detected in the colonic mucosa of rats treated with TMG. These results suggest that TMG is effective for the treatment of colitis in rats induced by TNBS.
DIFFERENT POSTING
For many years, there have been a small but vocal group of people advocating the use of Vitamin E (d-alpha-tocopherol) *as an enema* for the treatment of Ulcerative Colitis. Their results were all anecdotal, but exciting, and the medication-- which consisted of popping Vitamin E capsules and doing your best to emulsify with water as a carrier-- was cheap, easy to obtain, and potentially free of serious side effects (unknown).
Now a study released today actually PROVES there's significant merit in this therapy! Any weapon in the fight against UC is a big deal, and we should be thrilled at this simple but highly effective option for the more experimental colitis patients amongst us.
Be sure to note that while 100% (!) of people responded positively to the treatment after 3 months, it DID take 3 months, and they all used another pharmaceutical therapy (either 5-ASAs like Lialda or Asacol, or immunomodulators like Remicade).
Here's the study:
Rectal administration of d-alpha tocopherol for active ulcerative colitis: A preliminary report.
Department of Internal Medicine, Amir-Alam Hospital, North Sa'adi Street, Tehran 13145-784, Iran. mirbagherimd@yahoo.com.
AIM: To investigate the anti-oxidant and anti-neutrophil recruitment effects of rectal d-alpha (d-alpha) tocopherol administration on mild and moderately active ulcerative colitis (UC). METHODS: Fifteen patients with mild and moderately active ulcerative colitis were enrolled in an open-label study of d-alpha tocopherol enema (8000 U/d) for 12 wk. All patients were receiving concomitant therapy with 5-aminosalicylic acid derivatives (5-ASA) and/or immunomodulator medications. Endoscopic evaluation was performed at baseline and after 4th and 12th weeks. Disease activity was measured with the Mayo disease activity index (DAI) and remission was defined as DAI of <= 2 with no blood in stool. Clinical response was defined as a DAI reduction of >= 2. RESULTS: At the end of 12th week, the average DAI score significantly decreased compared to the beginning of the study (2.3 +/- 0.37 vs 8 +/- 0.48, P < 0.0001). One patient was withdrawn after 3 wk for being unavailable to follow-up. On the 4th week of therapy, 12 patients showed clinical response, 3 of whom (21.4%) achieving remission. After 12 wk, all 14 patients responded clinically to the therapy and remission was induced in 9 of them (64%). No patient reported adverse events or was hospitalized due to worsened disease activity. CONCLUSION: This preliminary report suggests that rectal d-alpha tocopherol may represent a novel therapy for mild and moderately active UC. The observed results might be due to the anti-inflammatory and anti-oxidative properties of vitamin E.
Flavonoids Found to Help Colorectal Health
By Greg Arnold, DC, CSCS, June 18, 2008, abstracted from “Dietary Flavonoids and Colorectal Adenoma Recurrence in the Polyp Prevention Trial” in the June 2008 issue of Cancer Epidemiology Biomarkers and Prevention
Colorectal cancer is the second leading cause of death from cancer (behind lung cancer) in the United States. It claims more than 55,000 Americans each year and poses a risk for nearly 1 in 4 Americans (80 to 90 million) because of age or other factors. It affects both men and women equally1.
Fortunately, a number of ways are available to help colon health, including calcium2, conjugated linoleic acid3, vitamin B64, green tea5, fiber6, olive oil7 apples8 and omega-3 fats9. Now a new study10 has found that flavonols, a group of over 5,000 compounds11 contained in almonds12 as well as fruits and vegetables13 that benefit colon health14, pancreas health15, and breast cell health16, may also help colorectal health.
In the study, researchers analyzed data on over 1,900 patients who participated in the Polyp Prevention Trail (PPT). This was a four-year randomized, multi-center, nutritional intervention trial that evaluated whether following a high-fiber diet (18 grams of fiber per 1,000 calories), high-fruit and high-vegetable (5 servings per day), and low-fat (no more than 20% of total calories) diet is effective in inhibiting colorectal adenoma recurrence17. The researchers found that total flavonoid intake did not significantly reduce the risk of having a recurrence of colorectal adenomas. However, there was a 36% reduced risk of having an advanced recurrence of adenomas in the highest flavonoid intake group (more than 106 mg per day) compared to the lowest intake (less than 51 mg per day).
When looking at specific flavonoids, they found that flavonols (more than 17.3 mg per day compared to less than 8.12 mg per day) and isoflavonoids (more than 0.133 mg per day compared to less than .045 mg per day) produced a 76% and 54% reduced risk of any recurrence, respectively. Flavonols are found mostly in apples, beans, broccoli, and onions while isoflavonoids are found mostly in bean and soy products.
For the researchers, “our data suggest that a flavonol-rich diet may decrease the risk of advanced adenoma recurrence.”
Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at http://www.CompleteChiropracticHealthcare.com
2 Meunier, P. J. (1999). "Calcium, vitamin D and vitamin K in the prevention of fractures due to osteoporosis." Osteoporos Int 9 Suppl 2: S48-52
3 Larsson SC. High-fat dairy food and conjugated linoleic acid intakes in relation to colorectal cancer incidence in the Swedish Mammography Cohort. Am J Clin Nutr 2005 82: 894-900
4 Theodoratou E. Dietary Vitamin B6 Intake and the Risk of Colorectal Cancer. Cancer Epidemiol Biomarkers Prev 2008 17: 171-182 doi: 10.1158/1055-9965.EPI-07-0621
5 Yong G. Prospective Cohort Study of Green Tea Consumption and Colorectal Cancer Risk in Women. Cancer Epidemiol Biomarkers Prev 2007 16: 1219-1223 doi: 10.1158/1055-9965.EPI-07-0097
6 Jacobs ET. Fiber, sex, and colorectal adenoma: results of a pooled analysis. Am. J. Clinical Nutrition, Feb 2006; 83: 343 – 349
7 Gill, C. I., A. Boyd, et al. (2005). "Potential anti-cancer effects of virgin olive oil phenols on colorectal carcinogenesis models in vitro." Int J Cancer 117(1): 1-7
8 Waldecker M. Histone-deacetylase inhibition and butyrate formation: Fecal slurry incubations with apple pectin and apple juice extracts. Nutrition 2008; 24(4): 366-374
9 Hall MN. A 22-year Prospective Study of Fish, n-3 Fatty Acid Intake, and Colorectal Cancer Risk in Men. Cancer Epidemiol Biomarkers Prev 2008 17: 1136-1143 doi: 10.1158/1055-9965.EPI-07-2803
10 Bobe G. Dietary Flavonoids and Colorectal Adenoma Recurrence in the Polyp Prevention Trial. Cancer Epidemiol Biomarkers Prev 2008 17: 1344-1353 doi: 10.1158/1055-9965.EPI-07-0747
11 Aherne SA, O'Brien NM. Dietary flavonols: chemistry, food content, and metabolism. Nutrition 2002;18:75–81
12 Milbury, P; Chen, CY; Dolnikowski, G; Blumberg, J; Determination of Flavonoids and Phenolics and Their Distribution in Almonds. J. Agric. Food Chem 2006; 54:5027-5033
13 Erdman JW Jr, Balentine D, Arab L, et al. Flavonoids and heart health: proceedings of the ILSI North America Flavonoids Workshop, May 31–June 1, 2005, Washington, DC. J Nutr (2007) 137:718S–37S
14 Rossi M. Flavonoids and Colorectal Cancer in Italy. Cancer Epidemiol Biomarkers Prev 2006 15: 1555-1558
15 Bobe G. Flavonoid Intake and Risk of Pancreatic Cancer in Male Smokers (Finland). Cancer Epidemiol Biomarkers Prev 2008 17: 553-562 doi: 10.1158/1055-9965.EPI-07-2523
16 Dietary flavonoid intake and Breast Cancer risk among women in the long island breast cancer study project”. Abstract #4014 at the 97th Annual Meeting of the American Association in Cancer Research.
17 Lanza E, Schatzkin A, Ballard-Barbash R, et al. The polyp prevention trial II: dietary intervention program and participant baseline dietary characteristics. Cancer Epidemiol Biomarkers Prev 1996;5:385–92
NEW POSTING
New fecal test for colon cancer
Colon Cancer
RanplexCRC is a diagnostic test that can detect 28 polymorphisms associated with colorectal cancer in a single stool sample. It does not require a hospital visit or dietary restrictions, while having greater sensitivity than the currently used Faecal Occult Blood (FOB) screening test. RanplexCRC may more accurately profile patients and reduce the number of patients for colonoscopy, saving time and resources and reducing patient discomfort.
Most sporadic colorectal cancers follow a well recognised progression from normal cells through adenoma (abnormal glandular growths) to cancer, driven by mutations in a small number of genes. RanplexCRC can simultaneously detect 28 mutations from four key genes in cancer or pre-cancer cells shed into the bowel. Selected mutations present in APC, KRAS, BRAF and Tp53, along with wild-type control sequences, are represented on 2 biochips detected using Randox's Biochip Array Analysers.
The Randox family of Biochip Array analysers are immunoassay testing platforms that work by combining panels of related tests on a single biochip. The chemiluminescent endpoint is detected by a CCD-camera and quantified by a custom image-processing software. Evidence, a fully automated analyser for high-throughput laboratories, and the Evidence Investigator, a semi-automated analyser for low-throughput laboratories and research purposes, are both available from Randox.
Bowel (colorectal) cancer is the second largest cause of cancer mortality in the western world, but up to 90% curable if detected early. Unfortunately, most patients present with advanced disease, reducing their long term survival. National Screening programmes are being introduced throughout Europe, to reduce CRC mortality, using the FOB test. This cheap and non-invasive test detects blood in stool samples, which may be an indication of a tumour. Patients with a positive FOB test are then referred for colonoscopy. The FOB test, however, suffers from poor sensitivity, as not all tumours bleed (false negative test) and not all stool-blood is derived from tumours (false positive test). Many patients (up to 50%) may therefore be sent for colonoscopies unnecessarily. Colonoscopies are invasive, involve dietary restrictions and require the presence of a surgeon, so an intermediate test would benefit both the patient and the healthcare system. RanplexCRC provides the answer, filtering out false positives.
About Randox
Randox is an international diagnostics company, headquartered in the UK. Randox develop, manufacture and market clinical diagnostic products worldwide. Core products are: Biochip Array Technology; clinical chemistry analysers and reagents; quality controls and EQA; environmental diagnostics; recombinant proteins and antibodies.
I feel stupid asking this question but your enema directions have me confused. Are you supposed to use the entire 1.5 tbs plus the vitamin E or just the top layer of vitamin E? I appreciate any clarification you could provide for me.
Hi Sheldon! First of all I want to thank you for posting your experience!!! If only more people would do that and experiment with safe treatments. I started using Vitamin E enema a week ago. 6 months ago they told me 80% of my intestines were inflamed. Was prescribed Prednisone and Salofalk and after coming off of prednisone the symptoms started returning slowly (no much stool form, a bit of bleeding). Eventually the bleeding got more and my doctor told me to start Salofalk enema. I thought let's try the vitamin e enema first Salofalk I can always try later.
After only 3 days all the symptoms disappeared. Not even a drop of blood. It's really amazing!!! You can imagine how thrilled I am:D I do have a question though how long was the treatment with 20 capsules? Do you know of anyone who's treated UC with 10? I don't want this coming back again I want to cure it!
I started my husband on the diet portion of the procedure on Tuesday. He was discharged from his 2nd hospital admission in 2 months on Saturday :( Surgery is way too close for comfort. He is eating 2 eggs per day, chicken, salmon, brown rice and steamed spinach, broccoli, brussel sprouts, carrots, and yellow squash. On Friday he started the enemas. I could not find an enema syringe, so I bought a disposable saline enema and emptied it and filled it with the distilled water and vitamin E. My question is; is this "good enough"? I see some residual vitamin E left in the enema. I want to make sure he is getting the good stuff (vitamin E) and not just the distilled water. Any advice/recommendations...
Also, can I season his food with anything? I have been using some garlic with the chicken (garlic being an anti-inflammatory) and turmeric with the salmon (for the anti-inflammatory properties). Some salt and pepper too.
He is improving (from the very poor state he was in). No or very little blood in the stool! Minimal urgency. Only 3-4 stools per day. The big thing is trying to eliminate the middle of the night stool as well as get some form (all still very watery).
He is currently on 40mg of prednisone (hope to start tapering in a couple weeks), weekly iron infusions (his h&h and iron levels are very low, he has had a total of 5 blood transfusions in the past 2 months), and Remicade infusions every 6 weeks. He takes 2 probiotics daily, 1 Vitamin E daily, 1 L-Glutamine and 1 Fish Oil daily.
I know English Poorly, and reading this forum it is hard for me because I ask.Can I do enema with vitamin E without the empty capsules, mix it only with distilled water or boiled into bulb? If you do not explain it to me, please.I need this answer for my friend.thanks!
If you cannot find liquid vitamin E, and you have to use vitamin E capsules, then you must either snip one end or use a sharp needle or straight pin to put a hole in one end and squeeze the contents into the enema bag. You don't put the capsules in the bag, you simply empty the contents of the vitamin e capsule into the bag with water -- bottled distilled is suggested.
Hi Lolite!
How much water with E 400 IU (glass of water)),how long hold it into colon (1 hour or all night)
In my country is't E that You suggest Is good d-alpha-tocopherol with purified soybean oil, gelatin, glycerol ?
Thank You !!!
I don't remember what Sheldon recommended but I seem to think it was not more than 1/2 - 1 cup water. I believe he said you should retain it as long as you could and even mentioned that he was able to retain it completely. Go back and re-read his posts.
Vitamin E is more theraputic and healing if you can get the complete form of it. A complete vitamin E supplement will list alpha, beta, delta and gama tochopherols and tocotrienols. Look for it on iherb.com. They ship overseas.
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Issue 64: Ulcerative Colitis Cure - Vitamin E Enema & Diet 
Re: Issue 64: Ulcerative Colitis Cure - Vitamin E Enema & Diet 
