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Just wondering if anyone else here is mercury toxic? (Not that you would necessarily know, but...). I'm trying to figure out if mercury toxicity causes TMAU.
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Trimethylaminuria
Mercury and TMAU?
PM #39736
Date: 5/28/2012 6:07:25 PM ( 12 mon ago )
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URL: http://curezone.com/forums/fm.asp?i=1944413
My TMAU started when I started Cutler's mercury chelation protocol with DMPS (I added ALA later). I know that DMPS is sulfury and sulfur makes TMAU worse, but the odor doesn't go away when I'm not on DMPS (although it is worse when I'm on it). I think it must be that either the DMPS itself somehow caused this, or the mercury being stirred up did. I think there is at least some link between mercury and TMAU because mercury apparently interferes with the conversion of riboflavin and folic acid to their active forms in the body, and I think both riboflavin and folic acid are needed for the enzymes that break down trimethylamine to work. Riboflavin and folic acid do reduce the odor for me, but they don't completely get rid of it and I can't take folic acid (or the active form, methylfolate) on a regular basis because it causes mercury-related side-effects for me.
This study (http://www.ncbi.nlm.nih.gov/pubmed/9750169) says that mercury chloride inhibited FMO3, which is the enzyme that breaks down trimethylamine...
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