Biological Research Record by Rosie
by rosieliu

Applications of proteinase K   54 d  
Proteinase K has lots of applications, and this article will show you the details.
 
Proteinase K, derived from Limbert Candida albicans, belongs to the class of serine proteases. Proteinase K has extremely high enzyme activity and wide substrate specificity, and can preferentially decompose the ester bonds and peptide bonds adjacent to the C-terminus of hydrophobic amino acids, sulfur-containing amino acids, and aromatic amino acids. It is active from pH4.0 to pH12.0, the optimum pH is between 7.5-8.0, and the optimum temperature is between 50-55℃. In the presence of 0.2-1% SDS or 10 mM urea, proteinase K showed higher activity, while the presence of commonly used ...   read more



 
Research Progress of Neutralizing Antibodies against Novel C   6 mon  
Neutralizing Antibodies as a new weapon to fight COVID-19 will play an important part in SARS-COV-2. This article will show you the mechanism.
 
The COVID-19 epidemic has become a global pandemic, causing great damage to the global economy and people's lives and health. At the same time, the scientific research personnel quickly carried out the research. Genetic analysis can reveal the source and evolution of the novel coronavirus, and can provide virologists to further discover the structure and function of various proteins of the novel coronavirus. Pathological studies provide information for formulating strategies to intervene in infection. COVID-19's strategy is being developed in preclinical and clinical research. An ...   read more



 
T cells targeting novel coronavirus   8 mon  
T cells targeting novel coronavirus were found in patients with new coronary pneumonia and uninfected patients
 
As we all know, T cells are white blood cells that play a vital role in the immune response. But in the fight against   read more



 
ACE2 Antibody and Novel Coronavirus   9 mon  
ACE2 is one of the hottest target of SARS-CoV-2 Invasion
 
On February 11, 2020, the novel coronavirus that raged for more than one month in China was officially named SARS-CoV-2 by the International Virus Classification Committee. From the nomenclature, it is not difficult to find that SARS-CoV-2 and SARS coronavirus, which were frightening 17 years ago, do have a deep origin: they are both coronaviruses and highly pathogenic. What exactly is this coronavirus? The so-called coronavirus refers to a group of viruses. It is named after a circle of nail-like protrusions (thorn protein) on the surface of the virus particles, which looks like a ...   read more



 
Contradictory functions of cancer of the same gene   13 mon  
Contradictory functions of cancer suppression and cancer promotion of the same gene
 
Overview of PTEN Research The PTEN gene is a tumor suppressor gene that is widely changed and closely related to tumorigenesis. This gene encodes the classic PTEN protein consisting of 403 amino acids. PTEN protein has phosphatase activity, which can inhibit the occurrence and development of tumors by antagonizing the activity of phosphorylases such as tyrosine kinase. PTEN proteins can enter the nucleus through multiple mechanisms. Nuclear PTEN can interact with a variety of proteins, affect the stability of the genome, etc., and exert a tumor-suppressive effect. The main ...   read more



 
Who is more likely to suffer from breast cancer?   15 mon  
Who is more likely to suffer from breast cancer? and how to prevent breast cancer.
 
Breast cancer is one of the most common malignant tumors in women all over the world. According to ASCO data, in 2019, an estimated 268,600 women in the United States will be diagnosed with invasive breast cancer, and 62,930 women will be diagnosed with in situ breast cancer. An estimated 2,670 men in the United States will be diagnosed with breast cancer. It is estimated that 42,260 deaths (41,760 women and 500 men) from breast cancer will occur. The data is terrifying. Who is more likely to suffer from breast cancer? Breast cancer occurs in middle-aged women between the ages ...   read more



 
 

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Articles in this blog will explain to you the mechanism of some disease & physiology phenomenon and show you the latest biological research of them. more...

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