this is just another topical that i would expect can work relatively well however, i've never personally tried it. i'm going to start using it before zix, i haven't decided on an official concentration yet. grape seed extract is an extremely powerful anti-oxidant, and can aid in the repair of blood vessels, much more powerful than vitamin C or E. anyway, here is a double-blind study.
Grape Seed - (in this study procyanidin was extracted
from apple but it is also main ingredient in GSE).
The first clinical trial of topical application of
procyanidin B-2 to investigate its potential as a hair
growing agent - Takahashi T, Kamimura A, Yokoo Y,
Honda S, Watanabe Y.
Procyanidin B-2 is a compound we have identified in
apple which acts as a growth-promoting factor on
murine hair epithelial cells. This report describes
our investigation of the hair-growing effects of 1%
procyanidin B-2 tonic after sequential use for 4
months. A double-blind clinical trial was performed,
involving a total of 29 subjects (procyanidin B-2, 19
men; placebo, 10 men). No adverse side effects were
observed in either group. In the procyanidin B-2
group, 78.9% showed an increased mean value of hair
diameter, whereas only 30.0% in the placebo group
showed any increase (p < 0.02, Fisher's exact
probability test). The increased ratio of hairs
measuring more than 40 microm in diameter after 4
months of procyanidin B-2 treatment was significantly
higher than that of the placebo controls (p < 0.05,
two-sample-t-test). The increase in number of total
hairs in the designated scalp area (0.25 cm(2)) of
procyanidin B-2 subjects after a 4 month trial was
significantly greater than that of the placebo
controls (procyanidin-B-2, 3.67 +/- 4.09 (mean +/-
SD)/0.25 cm(2); placebo, -2.54 +/- 4.00/0.25 cm(2); p
< 0.001, two-sample t-test).
Procyanidin B-2 therapy shows potential as a promising
cure for male pattern baldness.