I have psoriatic Arthritis and accidently discovered that grapeseed extract stops my tissue flares 100% after 3 days at 300mg. I don't get them at all if I stay on it. The same can be said for my Dad. When I first became ill, I could no longer turn my head or lift my right arm and nothing the docs gave me changed that, the tissue was so inflammed it dislocated mmy collar bone, tore my ac joint dislocated several ribs and facet joints. I simply woke up like that one morning. Talk about confusing! Anyway, months of no diagnosis and doctors acting like I had two heads I adjusted and I got use to it. One day I read an article on sun damage and grapeseed, so decided to try some. Instead, something wonderful happened. I woke up on day 3 pain free. I couldn't imagine it was the grapeseed so stopped it to see and in 3 days I couldn't move again. I of course started right back in it and told EVERYONE I knew to try it

I felt obligated to mention that over the years, I have suggested several friends try it for gout to see what would happen and was excited when all of them had the same results. It also took 3 days, but the dosage has also varied and worked even at 100mg. All have said it worked better than their prescriptions, with 100% relief by the 3rd day. Being guys they won't stay on it, but now pull it out at the first twinge and stop it in it's tracks.
Such a simple thing has made a huge difference in my quality of life and many others, so I really wanted to at least put it out there. I get mine cheap on ebay buying in bulk but I would think any good quality grapeseed should work.