I started taking grapefruit seed extract and it says to take a good probiotic with it. I researched, a little, and decided that Primal Defense looked good. After starting that, I researched more and discovered that the makers of Primal Defense suggest taking a round of their Fungal Defense first. I stopped the Primal and started a bottle of Fungal one week ago. I have taken probiotics before and have not noticed any 'die-off' or any other results for that matter. Well, something is going on now! I have been very tired, achy, foggy, etc. this past week. Just today, day 9, I finally feel better. YAY! It is a 2 week bottle. You work up to 8 tablets per day and maintain that for 1 week, then switch to Primal Defense. I am a veteran liver flusher and will do number 23 this coming week and hope to see some dead yeast flying out of me! LOL
Note: I ordered it from win-edge.com and saved a ton over what my local Wild Oats charged, even with shipping charges.
Hope this helps!