When I was taking the Coptis and/or Cucurma religiously several months ago to try to sleep through the night, it did not have that affect on me. I don't know that they kept me awake, but they did not help me sleep through the night, even though that was one of the reasons I was using them, as advertised on Julia Chang's website.
I don't always sleep through the night lately, but I do more that I had been several months ago. I think I am almost stone free after 12 liver flushes. E3live has also helped me sleep through the night a lot of times and dream very deeply. Right now, if I get up in the middle of the night - to go pee - I think it is because I am running too acidic and it is upsetting my would be interstitial cystitis. So back to alkalinizing.
Balance is the key.