So sorry...I misunderstood your question. It's best to take the bulking agent on an empty stomach...and at least an hour before food, supplements or medication. I usually take it first thing in the morning...after I've had some water...and then before I start preparing lunch or dinner or before bedtime.
Dry skin brushing is a great 'hobby'...there are wonderful benefits of that alone...silky skin with no need for lotions...and elimination of cellulite after you've done it for a while! It also really helps with the cleanse...you'll release more gunk!
Good luck with the cleanse!