A 12-year-old girl debilitated by cerebellar atrophy and ataxia was able to function again after taking high doses of coenzyme Q10 (CoQ10). The girl’s neurological disorder, characterized by the inability to coordinate gross and fine motor activities, was associated with CoQ10 deficiency.
Under the watchful eyes of researchers in Barcelona, Spain, the young girl was given 2,500 mg of CoQ10, divided into three daily doses, for three months. At six months the dose was reduced to 1,500 mg daily and at 12 months the dose was again cut to 1,000 mg daily.
Researchers noted that after three months of CoQ10 supplementation, the girl’s movement, gait, speech, handwriting and vision had improved. After 16 months, she was able to walk unaided and signs of cerebellar atrophy had disappeared.
The study gave researchers greater insight into some of the symptoms of CoQ10 deficiency. They concluded: “Clinical improvement after CoQ10 supplementation was remarkable, supporting the importance of an early diagnosis of this kind of disorder.”
Journal of Neurological Sciences 246:153-158, 2006