When I was at 10 drops I had feelings of slight burning when urinating. I've never (knock wood!) had a bladder infection, but I suspect that's what they feel like. I ended up with a very acidic state and a terrible gout attack the next day. My suspicions are that it was my bladder reacting to the high acid level in my body.
While I turned acidic, I believe it was due to the die-off of who knows what that was making that happen. I had the same thing happen during a parasite cleanse.