I tried doing the double 1/2 doses you suggested (6 drops in 6 oz juice, followed by another 6 drops in 6 oz juice). When I did this one time, in the evening, I was fine and able to get the 12 drops in this way. But, when I tried to do this morning and evening, I didn't do so well. I was fine at first, but the next day I was in the nausea and big D mode. I immediately backed off and did just 6 drops 1x yesterday and I feel fine today. I'm going to go back to 6 drops 2x starting today, but I'm not sure I can get beyond that!