I've been taking this for a week and have already noticed a significant improvement in the fluidity of my knees which normally feel compressed and snap a lot. My back also feels more flexible and no longer compressed. I bought this mixture of HA for the health of my eyes since I learned that the vitreous fluid in the eye is HA molecules. I hope this will improve the quality of the vitreous and perhaps reduce or eliminate floaters. I wish I had found out about this sooner.