I have them in my head and tissues from head to toes.....literally!! They are being hit and the thrashing is good. The stuff is hitting them then. The next step is they get hard or feels like they swell up....fun in the head! And then it seems like they start to get hard and they seem to feel crunchy and then they die and fade away or get consumed by the body. Sounds weird, but that is what I have experinced with Prazi and Lugols. It is just a process I need to got through to kill them. Right now I am at my last resort and this is working so far. But it is only day 1 and I have only used 1/2 a drop today. Got to take it easy when they are in my head. Hope this helps.