Yeah on the bottle it should list the recommended dosage. I've been told by my some of my previous doctors that it's generally best to take them immediately after meals rather than with them. But to really see the effects it is a good idea to also mix in a high fibre diet with the probiotics. This way your body is clearing all waste consistently and allows the probiotics to flourish. When I first went on them I would take two pills, twice daily with breakfast and dinner. You may also want to consider taking a green drink in the morning as it will also encourage healthy bacterial growth in your intestine. There are a bunch out there the most popular being the Greens+ brand but there are many others.