I gues in the case of my friend who is dealing with those problems the reason is exposure to heavy metals in childhood or later!?!
But we will have to check that by lab tests.
Than there is also challenge of chelating protocol.
I wonder if wheatgrass and barley juice could have also chelating function ( since there are a lot of amino-acids ).
I guess amino-acids and proteins are capable of binding the heavy metals in the blood and tissues.
And support this process with fermented cruciferous (broccoli, cauliflower, brussel sprouts ) vegetable with EM microorganism solution and garlic?
Beside this using nettle juice in smoothies with fruits.