I can only share my experience. I had 2 "punch biopsies" when I first contracted EC almost 4 years ago. The Dermatologist sent them away for analysis and whatever he was looking for i.e. cancer, was not found.....nor was a diagnosis. I was left with 2 white spots where the biopsies were done and my skin peels in the biopsy area just as the rest of my lips do. I will say the area was greatly traumatized at the time of the biopsies but my scabs were so thick and painful then. Now the area looks more like the rest of my lips.