My primary motivation in supplementing the Master-Cleanse is that, after about a week of cleansing, I’ve created a very inhospitable environment for parasites, fungus, and yeast ... so it would be an ideal time to go one step further and zap them.
But I see what you’re saying: the Master-Cleanse is a cleansing program, and nothing more. It is not designed to have any add-ons or supplements, and by even slightly altering the program, one risks defeating the entire premise of a cleanse.
Still, it would be nice to know if there are any extracts or supplements that are 100% guaranteed to not interfere with the MC. Or, better yet, are there any extracts or supplements that actually ENHANCE the Master-Cleanse ... But apparently the answer is "no."