I think that the 'genetic' component that people allude to is the fact that some people are able to have a vaccination and be unharmed by it while others incur quite a bit of damage. The 'genetic' component may be that some people's detoxification pathways are not as proficient as other's in eliminating the toxins from these vaccines quickly. These vaccines seem to damage the digestive tract, which is where approx 70% of the body's immunity resides.
For me, my eczema did not begin until I was subjected to the round of vaccinations that are required to begin school in Kindergarten. This was many decades ago before they began requiring so many vaccines at birth and a few short months afterward.
I remember clearly those days after my rounds of vaccines where my hands were tied to prevent me from scratching at my eczema. There were days upon days where I sat on the couch tied with cream slathered all over my breakouts. No one connected it with vaccinations at the time.
Now I know that the vaccines damaged my intestines and unbalanced my digestive tract, which led to leaky gut, which led to me becoming allergic to many foods, pollen and grasses. No one in my family suffered with eczema and allergies.
Later, I had a series of hepatitis-B vaccinations and for the first time, the eczema in the folds of my arms and legs became systemic and raged all over my body. I also experienced vertigo and itchiness and increased allergies.
I do believe that vaccinations harm some kids, resulting in learning and speech disorders, adhd, autism, eczema and allergies. It would be helpful if the scientific community found a way to test for sensitivities BEFORE administering these vaccines.