I don't know about the horse msm, I have never taken any of it. I take 1000 mg msm capsules from swansons. I take about five or six throughout the day, not all at once. Sometimes I do take two at the same time with no adverse reactions. There are several ways to make Colloidal Silver , you will need to research about how to make it on Google. I use three 9v batteries wired together to make mine. I never did buy one of the silver machines as I don't need it, the batteries work just fine. You must use .9999 silver wires and never sterling silver as it has other metals in it. The wires are expensive, but they last a very long time. Always use distilled water and never add anything else, no matter what do not add salt. This will make silver chloride and not Colloidal Silver . I think there is a silver forum on this site you could check out. Hope this helps! Good luck!