The nurse said my estradiol was low. I'm not sure that the other estrogens were tested. Thank you for this thorough post. This is actually all making sense to me, as my mother told me last night that my aunt had below average estrogen levels when she was around my age and had trouble getting pregnant. So, in my case, genetics is definitely a factor...along with environment toxicities that can be hard to avoid. And low libido for years...yep...