Trial run of doxycycline ok?

Is there any reason not to try doxycycline for 2 weeks for possible lyme's? I don't konw that I have lyme's but I do have some of the symptoms like cracking joints and fatigue and depression/anxiety. Never noticed a bite mark or rash but I do live in tick country. I have the oppurtunity to give it 2 week trial run so if I could get some feedback that would be helpful
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