I have started HW at night before. You just end up taking your last dose at night. Make sure you drink plenty of water because of the cayenne you may get heartburn if you don't. Sounds like you are loaded with Candidia Albicans. Almost sure you are loaded with parasites also if you have never done a parasite cleanse. Just make sure you understand what die off symptoms are. You probably won't get healed with one cleanse but keep going if you can and you won't regret it. It may take you around three HW cleanses to start seeing good results. HW is slow but safe and it works if you are faithful with it.