After battling with leishmaniasis (diffuse cutaneous) for 12 years I finally found the natural cure for it that isn't painful. You can painfully cure it by spraying refrigerant on it to freeze the sore and kill the parasite but it is definitely a hard way to go. I found that frankincense oil (Boswellia sacra) by Aura Cacia is 100% effective. Just apply it 2-3 times a day and within a few days the sore will be cured. Concerning the drugs: Glucantime (based on the heavy metal antimony) reduces cells uptake of Sugar but if you have heart problems it isn't recommended. I tried it and it made my heart hurt so I was afraid of getting a heart attack and so stopped it. Also the butt injection is the worst I've ever had. It's like the muscle reacts immediately against it. Imagine a very painful butt injection every day for a month. Miltefosine (pills) has a 95% cure rate and I tried it and it gave about 90% effectiveness but then the disease began to recuperate. It made me nauseous also. You can see all the info I have on this subject at http://www.dragonfly75.com/leish/leish.html