More on Dr. Koch...
"William F. Koch, a Detroit physician, theorized in 1919 that cancer was caused by a metabolic defect brought on by a single toxin produced by an injury or irritation. He proposed that toxins produced during metabolism and by bacteria were normally burned off during oxidation of carbohydrates. If the toxins persisted, they damaged the toxin-burning system and converted a normally present "harmless germ" into a virulent cancer-causing one. To cure cancer, Koch invented an "antitoxin to cancer" which he said was a mixture of an oxidizing catalyst he called glyoxylide (O=C=C=O) and a chemical called l:4 parabenzoquinone. A one-million-fold dilution  of this solution was given to patients by injection every six months, to "stimulate all the body's oxidation reactions to cure the cancer and a host of other diseases." Koch never revealed the process for the manufacture of glyoxylide, nor did he show it to exist.
Does Koch's glyoxylide exist? The molecule glyoxylide has been a subject of investigation by chemists including H. Staudinger in 1913  to Berson in 1986 . Recently Sulzle  reviewed the literature and considered the theoretical possibilities for the existence of a compound like glyoxylide. He found that all efforts to prepare, isolate, or chemically identify this compound failed. His studies on the theoretical physical chemistry of glyoxylide showed that the substance described by Koch cannot exist in nature. This, along with Jenssen's failure to find anything in Koch's "medicine" , confirms the conclusion that the glyoxylide which Koch claims to have invented did not exist." https://www.quackwatch.org/01QuackeryRelatedTopics/Cancer/oxygen.html
Glyoxylide is a dead end, and cannot be duplicated.