TH1 dominated conditions would include the following:
Diabetes type I
Multiple sclerosis Rheumatoid Arthritis
H. pylori infections
In the past, the management of immune conditions has usually involved the use of toxic drugs in order produce immunosuppression. Alternative therapies have looked at those natural remedies designed to strengthen the immune response, making one more resistant to disease. Now comes a new branch of immunology referred to as neuroimmunomodulatlon. This involves the use of naturally occurring substances able to normalize the immune response. In essence, taking a TH1 dominant state and pushing it to a Th2 state. The same would be true of a TH2 state being pushed to a TH1 state. Hence the result is TH1/Th2 balance.
Plant sterols are natural compounds found in edible vegetable oils. Although green and yellow vegetables contain significant amounts, their seeds concentrate the sterols. Most of the research on these phytonutrients has been done on the seeds of pumpkins, yams, soy, rice and herbs. Studies have shown that oral administration of plant sterols combined with plant enzymes is able to balance TH1 and TH2 cell types.