The latest research on Borrelia burgdorferi (Bb) shows that it exists in at least three different forms: the spirochete, the spheroplast (also known as L-form), and the cyst form. During the course of infection, Bb can shift among these three forms, converting from the spirochete form to the others when presented
with an unfavorable environment ( Antibiotics , changes in pH of body fluids in chronic inflammation, etc.), and reverting back to the spirochete form to grow and reproduce upon being released from naturally aging and dying infected cells. It is during the growth period after re-conversion to the spirochete form, as well as in adult spirochete form, that Bb is most vulnerable and susceptible to Antibiotics and natural elimination by the body’s immune system.
The severity of Lyme presentation is directly related to the spirochete load: low load results in mild or even asymptomatic infections. With increased spirochete load from subsequent repeated infections and/or reactivated dormant infections, the severity of the disease increases. Higher loads also impair key cells of the immune system and modify the immune response, thus making the immune system unable to fight the pathogen. The negative effects on the immune system increase the longer the spirochetes are present. To prevail in the effort to fight Lyme disease, it is necessary to not only restore the immune system to normal functioning, but to boost it as well. Even a normal functioning immune system is unable to attack and eliminate Bb in all its forms.
The results of research on Samento (TOA-free Chemotype Cat’s Claw) demonstrate its powerful immune system modulating and stimulating properties, along with pronounced anti-inflammatory, antioxidant, and anti-infectious effects. The diverse spectrum of the biological activities of Samento is due to its biologically active compounds. The pentacyclic oxindole alkaloids (POAs) contained in this Chemotype are generally accepted as the principal immunomodulating and immunostimulating agents. POAs are actively involved in the repair of many elements and functional mechanisms of both the innate and acquired immunity damaged by the Borrelia and other co-infections, assisting in restoration of structural and functional integrity of the immune system, enhancing its ability to eliminate the pathogens by natural way. In addition, this Chemotype contains quinovic acid glycosides – compounds with strong natural Antibiotic properties (the latest generations of conventional synthetic Antibiotics “Quinolones” are based on quinovic acid glycosides), which further enhance the medicinal effect of Samento in fighting the infection.
Considering the life-time of intracellular forms of Bb equivalent to the life-span of the cells invaded by these forms, they are constantly released into surrounding environment upon the natural cell death and destruction. The release of intracellular forms of Bb is gradual over the time due to various life-span of various invaded cells. Since about 90% of these forms are reside in various cells (including all blood cells) which have the life-span from 2-3 weeks to 6-8 months, it may be assumed that within a 6 to 8 month period, a significant majority of all intracellular form of Bb will be released into the environment where they can be successfully attacked by a properly functioning immune system and a natural powerful antibiotic.
Taking into account all the above, in can be assumed that continuous use of Samento over a period of time consistent with the life-span of several generations of various infected cells (8-12 months), would more likely result in gradual killing and eliminating of Borrelia and co-existing infectious pathogens, with subsequent reduction of infectious load in the body and restoration of the person’s health.
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I also took the liquid Samento, working up from 1 drop once a day to 5 drops three times a day. During that time, I experienced greatly elevated overall inflammation. On my doctor's recommendation, I started taking a curcumoid (derived from tumeric) product (Pure Encapsulation's Curcumin 97), one capsule 3 times a day. On the sixth day, someone asked me how the inflammation was - and I realized that the Samento-induced inflammation was completely gone.