I think its best to space the Vit C out since its water soluable and that way you have ample Vit C in your body at all times.
I take 5000mg Vit C myself because I also take higher Iodine - 100mg iodine/16 drops for almost three weeks now. 3000mg is what the BreastCancerChoices protocol suggests.
I do two salt loads daily to push out the bromide (up to 10-fold)and thus feel great all day. I do the first one early in the morning (5am) even before taking the first Lugol. I take Lugol about 1/2 hour later. I do a second salt load in the early afternoon (1pm) before lunch.