I had the same problem - could not take the 5 times a day. Dont think there is any harm in how long you take it. More like remebering to take and on empty stomach to get best results is more important here. I have read of poeple doing a year long program and taking echinacia as well and nothing bad has ever happened to them. Even a friend of mine in LA is doing the 30 day program just to do weight loss and just feel better is still doing it- on the 3 month as well.