increasing the amount of Iodine you ingest is a real personal call. it depends on your situation and what you are trying to accomplish. if you have nothing pressing, i think 50mg is a good place to stay at indefinitely. if you want to up it to see what your tolerence is, that might be useful to you as well. the amount of Iodine one can take seems to be a good realtime indicator of overall health and how far reaching your halogen imbalance is, if any.