Since pemphygus is an autoimmune disorder, I would first of all suggest making sure that your sister takes plenty of magnesium as magnesium deficiency has been strongly linked to immune/autoimmune disorders and it is estimated that anywhere from 70 to 95 percent of us are deficient in magnesium. Besides its many other essential benefits, magnesium is also a very good natural immune modulator.  You can find out information about other natural immune modulators here:

http://www.tbyil.com/Natural_Immune_Modulators.htm

As regards thalassemia, I am not sure that there is a cure for this mostly inherited condition but since it results in anemia you may find helpful information about correcting anemia here:

http://www.tbyil.com/Anemia.htm

Now, about those sugary drinks and the DVT:

Sugar is a blood vessel destroyer and is also unhealthy in many, many other ways - which explains why the World Health Organization has identified refined sugar as a number one cause of illness worldwide.

Cayenne pepper and vitamin C are both great for blood vessels.  Both are high in antioxidants and both also help thin the blood.

Other good natural blood thinners include:

Turmeric
Garlic
Onion
Bromelain
Water
Cinnamon
Dill
Oregano
Dried fruits and berries, such as raisins, cranberries, prunes and cherries
Vitamin B6
Vitamin E
Gingko biloba

Also, taking several digestive enzymes a few times daily on an empty stomach can help eliminate arterial plaque and dissolve blood clots.

Exercise is also among a natural blood thinner and it can be very helpful for conditions such as DVT

Compression stockings can also help relieve the symptoms of DVT

Another item well worth considering is a good blood tonic/blood cleanser.  My favorite is the Jon Barron fromula Blood Support Tonic available from Baseline Nutritionals.

I hope that helps,

DQ

I can't remember what website I was reading, but a chiropractor recommended vitamin E for his patient that was on coumadin.

The patient didn't want a confrontation from his dr, so he took both the E and coumadin and after his blood work, his dr had to take him off of the coumadin because his blood was getting too thin.