Everyone's cardiovascular system begins plunging at around age 30. By age 50, the levels of Nitric Oxide approaches zero, making us prone to heart attacks & strokes. You can reverse this deadly decline in Nitric Oxide by measuring your saliva with Nitric Oxide Test Strips, taking supplements & foods to boost your nitric oxide. Beet Juice is one of the best foods for this. See complete details here ( Save this link):
https://docs.google.com/document/d/1vpBf2OUlekJ1gjPy4G_SUSL5BLXc9rp0mO-4KTVuATA/edit#

Be very careful with niacin. Start with a SMALL dosage with meals and SLOWLY increase dosage to 1,500mg a day. If you take too much to start, you will feel like your skin is on fire for about 1/2 hr, called "Flushing."

See index to my research files here:
https://docs.google.com/document/d/1Zc1Foq1a-MnfARWYKDuax3mfaXu8Q8TtYdlmHqcr64I/edit#

My daughter in law's father died from a stroke at age 55, totally preventable by simply boosting Nitric Oxide levels in his blood stream. Everyone should take Nitric Oxide very seriously. Heart disease is a leading cause of death.

Grizz

My father and grandfather both died of circulatory disease before they reached 60 so I am at high risk. Neither of them were diabetic either which I am, therefore my risk is far greater. This is why I looked into all of this and why I do as much as possible to reduce my risk.

This post has grown a lot so the benefits will be missed by many who cannot be bothered to read it. I have kept it in sections with connected information.

You would benefit from large doses of daily Vitamin C to help repair your circulatory system. Absorption can be fairly poor so regular doses will be needed. Linus Pauling discovered that heart disease and stroke were caused by chronically low levels of vitamin C and supplementing with large doses resolved circulatory disease. Humans cannot manufacturer vitamin C unlike many animals so we need to consume it but the recommended amounts are far too low to prevent circulatory disease. This fact is all covered up by people who support the drugs industry and their false claim for cholesterol being the cause of heart disease which tries to promote the usage of statins. You might of heard about the news that they found a drug which is more effective (potentially more profitable) than commonly used statins if they continue to promote this myth and lies. Cholesterol serves a purpose, it is MEANT to plug the holes in the circulatory system as well as promote the repair of the brain and nervous system among other things but this only happens when there is insufficient Vitamin C. Animals that naturally produce vitamin C make large amounts of vitamin C, around 20 grams/day for some animals whereas the human RDA is set at a lowly 60mg! 60mg is believed to be the amount required to prevent scurvy! It is not the amount required to prevent circulatory disease which is a prolonged vitamin c deficiency. A human has a larger body and yet a fraction of the vitamin C is said to be needed. The human body can reactivate/recycle vitamin C to some degree but 60mg is still no where near enough. Smoking uses up large amounts of vitamin c which is why it can lead to heart disease.

You could try lyposomal vitamin C which improves vitamin C absorption quite dramatically. There has been a link to a website posted to this forum and is available on the vitamincfoundation forum. It gives instructions on the best way to make lyposomal vitamin C. You can purchase commercial lyposomal C from a few different manufacturers but it is fairly expensive so making it could be more cost effective. I would like to try this myself but ATM I have other things which are more important. Lyposomal C requires an ultrasonic cleaner to make the highest quality lyposomal c and the better ones of sufficient size are fairly expensive. A reasonable one costs around £170 but much better ones, such as the one that the person who details the process of making lyposomal c purchased one which costs over £1000. I found a better one than that for around £500. Better as in more utrasonic power which is important to effectively creating lyposomal c especially if it is stored inside a borosilicate glass beaker which absorbs a lot of the energy. BTW his utrasonic cleaner has 150 to 180 (with it's pulse active) watts of ultrasonic power whereas the £170 one has 180 watts. There are a few others in the 180 to 200 watt range but none come close to 240 watts of the James 6 MX. The only thing that it does not have, unlike the Elmasonic, is multiple frequencies which is less important for lyposomal creation. It's nice, if I had the money I would buy one but ATM £170 is about what I could afford, but it would be a compromise IMO and would not do the job as effectively. I am still considering what to do on this, £500 is a lot of money. However money is not much use to me if I am dead. Something that I want to avoid for as long as possible.

Other things which can be very helpful are anthocyanidins/proanthocyanidins which are provided by many fruits and plants. These provide natural blue/red/black colours to plants and are present in berries in particular. Blueberries, blackberries, currents and similar fruits provide quite large amounts. These colourings strengthen the circulatory system, skin and bones.
One thing you need to be careful about is the high carbs contained in berries because raising blood glucose does negatively affect vitamin c usage by the body. This is a big problem for diabetics and a reason why diabetics are prone to circulatory disease, but can even affect none diabetics if they consume large amounts of concentrated carbohydrates. You can get Grape Seed Extract capsules and power which is high in OPC's which can be beneficial. I use this myself. It has a terrible mouth feel because it is highly astringent. Powder is fairly inexpensive but encapsulating it would be an advantage if you cannot tolerate it mixed in water. Did I warn you about the astringency? lmao Yuck. BTW a lower carb diet might be helpful, at least staying off concentrated sugars and starches.

Another thing which might be worth you investigating is your folate metabolism. Folate is required for homocysteine conversion and therefore any faults with folate metabolism can cause raised homocysteine levels. I believe that this could be why my father and grandfather both died early. There are folate polymorphisms which can badly affect folate metabolism making some people more prone to circulatory disease amongst other things. The severity and combination of gene polymorphisms can have dramatic effects. Note that research gives mixed results and is not all that reliable IMO and reading between the lines I suspect that this is because of the form of folate used, some research could of used synthetic folic acid while other research using natural folates with mixed samples of genetic polymorphisms. It is known that some people with folate metabolism problems have big problems with folic acid where it badly affects normal folate usage causing a functional folate deficiency and this could explain the differences in some research studies.

For example if research gave folic acid to a group of people and followed outcomes and did not do genetic testing on folate metabolism. Some could have their circulatory systems damaged by the folic acid preventing their bodies from making use of the more limit quantities of natural folates while they are unable to convert the unnatural folic acid into the usable form. Whereas the people with more beneficial folate metabolism who could convert the folic acid to usable forms
which provided benefit. Some could die while the others could have benefit but overall there would be no significant improvement. This is why I hate research because it can be so easily manipulated to further a desired outcome, most likely profit. Unlike many people on forums who seem to enjoy posting useless links to research and are slaves to it, I am very sceptical about research and give little regard to it.

Making sure that this is working as well as possible should make sure everything is working optimally. These genes can be checked to find out how you are affected and what you need to do to make everything work as well as possible such as favouring certain foods and avoiding others.
https://www.23andme.com/
That site provides the testing and other sites can do the analysis and provide the information on how it affects you. If you search for 23andme and various things such as analysis etc then it should show the sites that can analyse the results which you can upload.

Pyridoxal-5-phosphate/vit b6 is important to the function of the transsulfuration pathway, conversion of the damaging homocysteine back to usable amino acids. Serine amino acid is also required. Which goes back to diet and the foods a person eats to ensure that things are working optimally as possible.

I use Magnesium carbonate which is fairly inexpensive and mix it with ascorbic acid which reacts in an acid/base reaction to form the magnesium salt magnesium ascorbate which is better absorbed and much more alkaline than the acidic ascorbic acid. It's easier on the stomach. This provided very important Magnesium and Vitamin C.

Another part of the expanded Linus Paulin Therapy is Lysine and Proline amino acids. You can read about these and their effects in the pdfs. BTW I found these on the vitamincfoundation forum but saving you time searching for them I have linked them here as I did upload them for someone else previously.

http://www.mediafire.com/file/z4vvwyyt4vf32en/Pauling_Therapy.7z

You can get many of these things in powdered form, such as ascorbic acid, lysine, proline which is a little more difficult to get. Body building suppliers sell a lot of it except for maybe proline. Buying larger quantities keeps the cost down rather than buying expensive capsules with limited quantities.

There are other nutrients which can also help. Vitamin K2 being very helpful as it makes sure that calcium goes to the bones rather than being deposited into the circulatory system. There are a few others which are explained in the pdf.

Serrapeptase as already mentioned, Nattokinase (From Japanese Natto) this can lower blood pressure, Lumbrokinase are all enzymes which can help to remove deposits from the arteries.

http://www.vitamincfoundation.org/forum/
http://www.qualityliposomalc.com/

One last tip, ensure that your stomach is functioning 100% because it can affect health in important ways including influencing methylation processes which can play a part in elevation of harmful products of metabolism. This can happen with increasing age because infections become more likely making adverse processes far more likely. Test stomach acid and ensure it is working 100% effectively. Ensuring stomach acid is working can be far easier said than done as I have found.

Verify that anything you take is safe and that it will not have any adverse effects on any medication that you take as some could conflict with blood thinners or blood pressure medication. The vitamincfoundation forum can give advice on some medications and possible conflicts.

I hope this is of some help and provides you ideas to research on.