I'm a big fan of what I like to call "no downside" (ND) supplementation. My wife has had some abdominal pain, so I suggest that she do a liver cleanse according to the old Lahey clininc methods. In the worst case, she is inconvenienced a few hours time and in the best case, it makes her pain go away and possibly saves her gall bladder, all for about $8 in raw materials.

It's hard to know the answer to the question you've posed above, since there are so many possible variables, it becomes as a Sherlock Holmes mystery. It might be that there is mucoid plaque on the small intestine, which is effectively preventing essential nutrients from being absorbed, which snowballs to give the symptoms you describe. The okra pepsin E3 can clean the small intestine, and is a "ND" supplementation. That's just one example. I'm starting to believe that Iodine is also an ND supplementation. I think people with mysterious "problems" can eventually benefit from going through a series of ND supplementations, provided all else is good, like , they're not eating poisons and are eating an otherwise healthy diet.