I'm glad you posted that about Shirley's Wellness Cafe. I used to go on there a lot and actually bought the Transfer Factor (used on the cat with renal failure on the site) when Haley's first blood work showed her BUN in the high normal range. I started a couple new things at the same time, and she started pooping in the house during the day while I was at work. I stopped all of the new stuff and she was fine again. I just never got back to adding in the Transfer Factor. I kept it in the refrigerator and started taking it myself. I still had the bottle in the fridge, along with a couple bottles of probiotics. I just checked and the Transfer Factor bottle is empty (except for the little packet in it to keep out moisture). I just ordered it again to try on Haley. Hopefully that wasn't the supplement that caused her to go to the bathroom before.