Thank you. The doctors don't know what could have caused this. My brother has never smoked and has always been very athletic. He does drink usually just on the weekends. One of the things that may have caused it is that he does not eat many fruits and vegetables. Prior to his diagnosis, he had been going to the doctor to find out why he has severe headaches. They do not think the headaches were related to the cancer. His first signs of illness were nausesness and he had become very weak. The only two types of cancer that family members have had are lung and prostate. I hope this helps.